Cellular Basis of Working Memory at a High Spatial Resolution

Cellular basis of working memory

In the presence of normal sensory and motor capacity, intelligent behavior is widely acknowledged to develop from the interaction of short-and long-term memory. While the behavioral, cellular, and molecular underpinnings of the long-term memory process have long been associated with the hippocampal formation, and this structure has become a major model system for the study of memory, the neural...

High temporal resolution imaging of spatial working memory

A substantial literature examining the neural correlates of workingmemory using functional magnetic resonance imaging (fMRI) has revealed the involvement of a predominantly fronto–parietal network in the maintenance and manipulation of information in working memory. However, the temporal dynamics of activity in this system cannot be revealed by fMRI at the sub-second level. We employed magnetoe...

A neural circuit basis for spatial working memory.

The maintenance of a mental image in memory over a time scale of seconds is mediated by the persistent discharges of neurons in a distributed brain network. The representation of the spatial location of a remembered visual stimulus has been studied most extensively and provides the best-understood model of how mnemonic information is encoded in the brain. Neural correlates of spatial working me...

Visuo-spatial Working Memory

Massive Molecular Outflows at High Spatial Resolution

We present high-spatial resolution Plateau de Bure Interferometer CO(2–1) and SiO(2–1) observations of one intermediate-mass and one high-mass star-forming region. The intermediate-mass region IRAS 20293+3952 exhibits four molecular outflows, one being as collimated as the highly collimated jet-like out-flows observed in low-mass star formation sources. Furthermore, comparing the data with addi...